Goat Secondary Antibodies
Cayman Chemical (R)-Cetirizine (hydrochloride), Purity: ≥98%, CAS: 130018-87-0, 250 mg
A selective histamine H1 receptor antagonist; the (R)-enantiomer of cetirizine; binds to the H1 receptor with higher affinity than cetirizine (Kis = 3 and 6 nM, respectively) and is highly selective for H1 over M1-M5 receptors; decreases production of RANTES and eotaxin following antigen stimulation in mouse eosinophils in vitro (MEC = 0.05 µM); dose-dependently decreases histamine-induced nasal rubbing and sneezing in mice (0.01-1% solution)
Cayman Chemical 17-phenyl trinor Prostaglandin F2α glycinamide methyl ester, Purity: ≥98%, 1 mg
A derivative of 17-phenyl trinor PGF2α ethyl amide
Cayman Chemical 5α,6α-epoxy Cholestanol, Purity: ≥95%, CAS: 1250-95-9, 250 mg
An oxysterol and an oxidative metabolite of cholesterol; accumulates in MCF-7 breast cancer cells following tamoxifen and PBPE application and induces triacylglycerol biosynthesis by binding to LXRβ; levels are increased in rat aorta and mesenteric artery following orchidectomy; levels are increased in post-mortem frontal and occipital cortex of patients with Alzheimer’s disease
Cayman Chemical PACAP6-27humnchIcken500ug
A PACAP receptor antagonist (IC50s = 1,500, 600, and 300 nM, respectively, for rat PAC1, rat VPAC1, and human VPAC2 recombinant receptors); binds to PACAP receptors on SH-SY5Y and SK-N-MC human neuroblastoma and T47D human breast cancer cells (IC50s = 24.5, 106, and 105 nM, respectively); inhibits PACAP (1-38)-stimulated cAMP accumulation in SH-SY5Y, SK-N-MC, and T47D cells (Kis = 457, 102, and 283 nM, respectively); inhibits vasodilation of pial arterioles induced by PACAP (1-27) and PACAP (1-38) in newborn pigs (10 μM); inhibits PACAP (1-27)-stimulated increases in plasma insulin and glucagon levels and pancreatic venous blood flow in dogs (500 μg administered locally to the pancreas)
Cayman Chemical Carbinoxamine (maleate), Purity: ≥98%, CAS: 3505-38-2, 10 g
A histamine H1 receptor antagonist (Ki = 2.3 nM) and first generation antihistamine; competes with [3H]diltiazem for binding to the benzothiazepine site on rat cardiomyocytes (Ki = 1.08 nM); decreases negative inotropic activity in isolated guinea pig left atria by 76% (EC50 = 250 nM); decreases negative chronotropic activity in guinea pig spontaneously beating isolated right atria by 48%
Cayman Chemical Pyridostigmine (bromide), Purity: ≥98%, CAS: 101-26-8, 500 mg
An inhibitor of AChE and BChE (IC50s = 0.35 and 1 μM, respectively, for the human enzymes); reduces organophosphate pesticide-induced decreases in AChE activity at 10 µM; reduces soman-induced membrane depolarization and decreases in AChE activity in isolated human muscle bundles in a concentration-dependent manner; prevents tachycardia and increases in sympathetic tone in mice following myocardial infarction induced by left coronary artery ligation at 3 mg/kg per day for four weeks
Cayman Chemical Cacodylic Acid (sodium salt hydrate), Purity: ≥95%, CAS: 6131-99-3, 50 g
A reagent used in electron microscopy techniques; has been used to introduce arsenic into proteins for SAD phasing in protein crystallography; has been used as an herbicide/defoliant; increases the likelihood of tumor formation in rats exposed to carcinogens at concentrations as low as 50 ppm
American Research Products Inc Anti PRSS56 Antibody
Anti-PRSS56 Rabbit Polyclonal Antibody Catalytic domain
American Research Products Inc Anti CTSZ Antibody
Anti-CTSZ Rabbit Polyclonal Antibody Propeptide domain
American Research Products Inc Anti HMCN1 Antibody
Anti-HMCN1 Rabbit Polyclonal Antibody Calcium-Binding EGF-Like Domain
American Research Products Inc Anti KLK10 Antibody
Anti-KLK10 Rabbit Polyclonal Antibody Kallikrein loop
American Research Products Inc Anti CPO Antibody
Anti-CPO Rabbit Polyclonal Antibody amino end of the catalytic domain
Cayman Chemical Hexamethonium (bromide), Purity: ≥98%, CAS: 55-97-0, 100 g
A nondepolarizing neuromuscular blocking agent; an nAChR receptor antagonist; decreases acetylcholine release induced by carbamoylcholine in isolated cat superior cervical ganglion at 27.4 and 54.8 µg/ml; decreases mean arterial pressure in unanesthetized rats at 40 mg/kg; induces signs of nicotine abstinence in nicotine-dependent rats when administered at a dose of 18 ng, i.c.v.
Cayman Chemical Amylin (1-13) (human, mouse, rat), (trifluoroacetate salt), Purity: ≥95%, 1 mg
A peptide fragment of amylin
Cayman Chemical Balofloxacin, Purity: ≥98%, CAS: 127294-70-6, 5 g
A fluoroquinolone antibiotic; active against clinical isolates of a variety of Gram-positive and Gram-negative bacteria in vitro, including K. pneumoniae, H. influenzae, N. gonorrhoeae, P. mirabilis, S. pyogenes, and MRSA (MIC50s = 0.025-0.78 μg/ml); inhibits DNA gyrase from E. coli, P. aeruginosa, and S. aureus (IC50s = 0.47, 11.0, and 2.5 μg/ml, respectively, in a DNA supercoiling assay); reduces mortality in mouse models of systemic S. aureus, MRSA, S. pneumoniae, K. pneumoniae, and P. aeruginosa infection (ED50s = 5, 20, 10, 160, and 50.4 mg/kg, respectively)